New

Research Scientist I - Khalil Lab

Broad Institute
paid time off, paid holidays, 401(k), retirement plan
United States, Massachusetts, Cambridge
Mar 17, 2026
Description & Requirements The Broad Institute of MIT and Harvard is one of the world's leading biomedical research institutes. It seeks to discover the molecular basis of major human diseases, develop effective new approaches to diagnostics and therapeutics, and disseminate discoveries, tools, methods, and data openly to the entire scientific community. Founded in 2004, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities, with collaborations spanning the globe. This Research Scientist position in the Khalil Lab at the Broad Institute will conduct cutting-edge research at the intersection of synthetic biology, immunology, therapeutics, and cell engineering. Primary Job Responsibilities: Responsible for designing and conducting moderate scope research and experiments. More specifically, the Research Scientist will develop and test therapeutic gene circuits for controlling and enhancing anti-tumor responses of primary immune cells, including T cells and macrophages. Specific activities will include molecular cloning, protein design, designing and building genetic circuits, lentiviral transduction of immune cells, immune profiling, and in vivo tumor models. Works within broad guidelines and policies. Contribute substantively to the writing and preparation of high-impact manuscripts, grant proposals, and community resources. Qualifications: A PhD in Neuroscience, Biology, immunology, or a related scientific discipline. 1+ years of related experience is preferred; this may include post-doctoral experience. As an independent scientific thinker, able to independently develop research concepts and design experiments. Must be forward-thinking and highly innovative, with a nimble scientific/technical mind, able to rapidly develop and execute on creative solutions to technical roadblocks. Strong ability to work both independently and collaboratively. Proven experience working effectively across experimental and computational research groups in a fast-paced, matrixed environment. Excellent written and verbal communication skills, especially the ability to clearly and concisely describe complex experimental methods and interpret results to diverse audiences. Ability to thrive in a fast-paced, rapidly changing environment. The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law. At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits. The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations. Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.