Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 95 |
Sr. Director, U.S. Commercial and Marketing Technology
Cambridge, Massachusetts
Location: Cambridge, MA (Hybrid role; 3 days/week onsite) Reports to: Executive Director, Commercial & Development Technologies Overview Alnylam is the world's leading RNA interference (RNAi) company, pioneering the development of novel the...
16h
| Job Type | Full Time |
Director, Strategic Account Lead - Northern California
Cambridge, Massachusetts
Overview The Strategic Account Lead (SAL) roleleads strategic engagement and contracting with target key accounts in order to drive growth, revenue, and joint value creation for Alnylam and the customer by enabling and optimizingaccess toAl...
16h
| Job Type | Full Time |
Senior Director, IT Finance Leader
Cambridge, Massachusetts
Overview: We are seeking a strategic, results-driven IT leader to own the technology vision and execution for Finance. This leader will serve as a crucial bridge between technical capabilities and strategic business needs, partnering direct...
1d
| Job Type | Full Time |
Director, Global Investigations and Enterprise Risk Management, Ethics & Compliance
Cambridge, Massachusetts
Overview Reporting to the Head of Global Investigations & Enterprise Risk Management, the Director, Ethics & Compliance, is responsible for managing all aspects of Alnylam's global investigations in all markets, including conducting and rep...
1d
| Job Type | Full Time |
Principal Associate Scientist, Biology
Cambridge, Massachusetts
Overview We are seeking a highly motivated and skilled Principal Associate Scientist to join our innovative Research & Development (ReDev) team focused on advancing next-generation oligonucleotide-based therapeutics. The ideal candidate wil...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: Alnylam is seeking a progressive, dynamic, business-focused HR Business Partner to support several Commercial leaders and their teams. Reporting to the VP HR, Commercial, this HR Business Partner will play a key role in delivering...
1d
| Job Type | Full Time |
Sr. Scientist, Pharmacometrics
Cambridge, Massachusetts
Senior Scientist - Quantitative Systems Pharmacology (QSP) Modeling Position Summary The Senior Scientist, QSP Modeling will develop and apply mechanistic quantitative systems pharmacology models to support drug discovery and development. T...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Senior Internal Auditor Overview We are seeking a Senior Internal Auditor to be a key contributing member of the Internal Audit function for one of Cambridge's most innovative, publicly traded biotech companies. The ideal candidate for this...
1d
| Job Type | Full Time |
Associate Director, Omnichannel Operations (US TTR)
Cambridge, Massachusetts
Overview The Associate Director, Omnichannel Operations (US TTR) is responsible for end-to-end operational delivery of omnichannel execution for TTR brands in the United States. This role ensures that U.S. omnichannel activity-across email,...
3d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The Senior Process Engineer will support R&D, CMC, GMP & non-GMP operations, CMO/CDMO operations, including new construction and upgrades to existing facilities, infrastructure, systems and equipment/instruments. The role will be r...
3d
| Job Type | Full Time |